Gene Expression in Liver

There is a higher genetic diversity in tumour cells which holds at the gene expression level. Through knowing the gene expression level we can regulate the hepatocellular carcinoma during hepatitis viral infection. Disease progression in HBV and HCV induced can influence by both environmental factors and genetic risk factors. Nucleic acid mediated gene therapy has been undergoing clinical trials which may result towards prevention of chronic liver diseases by regulating mechanism of different proteins expression using miRNA overexpression and mRNA functional silencing.

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