Ragaey Ahmad
Beni-suef University, Egypt
Title: Prevalence of Microscopic colitis in patients with Diarrhea-predominant Irritable bowel syndrome
Biography
Biography: Ragaey Ahmad
Abstract
Background: Irritable bowel syndrome (IBS) is one of the mostcommon functional gastrointestinal disorders. Properly diagnosing IBS can be challenging and uncertain as there is no clinical, biological orendoscopic marker for IBS. One gastrointestinal disorder frequently misdiagnosed as irritable bowel syndrome is microscopic colitis (MC). Thus, differentiating patients with diarrhea predominant IBS from those with microscopic colitis can be challenging as MC and IBS-D have similar symptoms.\\\\\\\\r\\\\\\\\n\\\\\\\\r\\\\\\\\nObjective: Our study is aiming to estimate the prevalence of microscopic colitis in patients diagnosed with diarrhea predominant-IBS according to Rome III criteria.\\\\\\\\r\\\\\\\\n\\\\\\\\r\\\\\\\\nMethods: Our study was designed in Beni-Suef university hospital in the period between February 2013 to December 2014. Patient was diagnosed as IBS according to the Rome III criteria. All patients were undergone fullhistory taking, clinical examination, laboratory investigations, abdomino pelvic ultrasonography, upper GIT endoscopy & colonoscopy with multiple biopsies for histopathological examination.\\\\\\\\r\\\\\\\\n\\\\\\\\r\\\\\\\\nResults: The prevalence of MC was 21% (15/120 CC & 11/120 LC).Duration of diarrhea was significantly higher in MC patients. MC was significantly associated with certain drugs and concomitant diseases.\\\\\\\\\\\\\\\\r\\\\\\\\\\\\\\\\n\\\\\\\\\\\\\\\\r\\\\\\\\\\\\\\\\nConclusion: Rome III criteria is not sufficient for exclusion of MC. Total colonoscopy with multiple biopsies from normal appearing mucosa is recommended for every patient previously thought to have IBS-D to exclude MC.