11^th Global Gastroenterologists Meeting

Biography

Biography: Bulent Calik

Abstract

This study is a review of the literature related to acute pancreatitis in Turkey. In order to find the published reports on this subject, national database (Tübitak Ulakbim Turkish Medical Literature database, http://www.turkishmedline.com, and two international databases [Index Medicus and Science Citation Index (SCI)-expanded] were searched. Key words for national database were acute pancreatitis, akut pankreatit and the key words for index medicus and SCI-e were acute pancreatitis and Turkey. More than three published case reports were included. Data for 959 patients with acute pancreatitis were obtained from 13 reports. Of the patients, 381 (40%) were males and 578 (60%) females. Their ages ranged from 16 to 107 years. Etiological factors were biliary in 674 (70%), alcohol in 70 (7%), hyperlipidemia in 40 (4%), diuretic usage in 12 (1%) and trauma in 11 (1%). 152 of all patients (16%) etiology were non-specific. Mortality was seen in 128 cases (13%). 265 (28%) patients had necrotizing pancreatitis. Of these necrosis rate is less than 30% in 76 (29%), 30-50% in 70 (26%), 50% in 107 (40%) patients. 12 patients (5%) had extra-pancreatic necrosis. 49 patients (5%) had abscesses in abdomen, 35 patients (4%) had pancreatic fistula, 16 patients (2%) had pseudocyst, 12 patients (1%) had bleeding into the abdomen, 10 patients (1%) had bile fistula, 10 patients (1%) had enterocutaneous fistula and seven patients (1%) had pancreatic abscesses. 12 patients (1%) had endocrine pancreatic insufficiency, three patients (0.3%) had exocrine pancreatic insufficiency. 59 of all patients (6%) developed multiple organ failure. Relaparotomy was performed in 19 patients (7%) with necrotic pancreatitis. Despite continuing technological advances in diagnosis and treatment, acute pancreatitis remains a disease with high morbidity and mortality.