6^th Global Gastroenterologists Meeting

Biography

Biography: Mona El-Amir

Abstract

In the absence of cadaveric donor liver transplantation ,living-donor liver transplantation (LDLT) is an alternative option for patients with end-stage liver disease .LDLT continues to be a life-saving option in counteries without satisfactory cadaveric donation.In our country the cadaveric donation is still limited by religious and cultural beliefs ,as in Japan ,Korea and India. We report the outcome of 120 adult LDLTs at Cairo University Trasplant Center.Patients records were retrospectively reviewed between 2006 and 2014 for recipient survival and complications.Trasplant recipients consisted of 110 men and 10 women (ages 19 to 62 years).The main indication for LDLT was hepatitis C cirrohsis , 110 patients ( 61.9 %). All procedures were right lobe hepatectomy without middle hepatic vein..All donors survived the procedure..Sixty four of 120 LDLT recipients are alive. Thirty patients died in the early(1st 3 months) postopeerative period ( 25%) because of (infections ,vascular complications, biliary complications, CVA , pulmonary embolism ). One-year survival is 64%%. HCV recurrence occured in 61 patients ( 50.8%) .Biliary complications developed in 47 recipients (39% ) ,most of them was treated by interventional teqniques.Vascular complications occured im 12 patients (10%).Thirty eight patients suffered from infections ( 31.6%).Acute rejection occured in 21 patients (17.5%) while chronic rejection developed in 7 patients (5.8%). Our results indicate that LDLT is with rather satisfactory outcome in absence of cadaveric donation.